Tottenham predicted to edge Villarreal 2-1 as Champions League opener kicks off Tuesday at 8pm BST; Frank’s injury-hit Spurs launch campaign at home, Villarreal without key men. Odds favour Spurs. Watch on Amazon Prime stream. First ever competitive meeting in Europe under new league format…

News (≈700 words):

Tottenham Hotspur host Villarreal in their Champions League opener on Tuesday, 16 September 2025, with kick-off scheduled for 8:00pm BST at the Tottenham Hotspur Stadium. (MightyTips)

TV & Live Stream

The match will be broadcast live on Amazon Prime Video for viewers in the UK. (Racing Post) For many fans, a free trial option may be available for Amazon Prime, making access easier. (The Standard) Coverage is expected to begin about an hour or more before kick-off, with pre-match build-up and possible team news. (The Standard)

Team News

Tottenham are grappling with a number of absentees. Key players such as Dominic Solanke remain sidelined with an ankle injury, while Yves Bissouma, Dejan Kulusevski, James Maddison, Radu Dragusin, and Kota Takai are also unavailable. (The Standard) Mathys Tel isn’t included in Spurs’ Champions League squad. (The Standard)

On the other hand, Randal Kolo Muani may make his Spurs debut, having been loaned in from PSG. (The Standard) There are choices to make in midfield, particularly in the No.10 role, where Xavi Simons and Lucas Bergvall are in contention. (The Standard)

For Villarreal, the injury list includes Willy Kambwala, Gerard Moreno, and Pau Cabanes. (Racing Post) Some defensive options are also missing, which might force Marcelino to adjust his back-line. (Racing Post) One interesting subplot: former Spurs defender Juan Foyth is expected to start for Villarreal. (Racing Post)

H2H (Head-to-Head)

This will be the first competitive meeting between Tottenham Hotspur and Villarreal. (The Standard) Both clubs have not faced each other in previous Champions League or European Cup matches in a competitive fixture. (The Standard)

Prediction

Tottenham enter the contest in decent form, having started their domestic campaign strongly. Under new manager Thomas Frank, they’ve collected good results (including wins over West Ham and Manchester City) and look confident. (Racing Post)

Villarreal have had a mixed start to La Liga, with some convincing wins at home but vulnerabilities showing when away. Their squad issues, especially in attack and defence, may make things difficult. (Racing Post)

Given these factors, many pundits and betting sites predict a tight match, likely with Tottenham winning 2-1. (The Standard)

Odds

• Tottenham to win: around 1.80 to 1.90 (≈ -0.5 handicap) depending on bookmaker. (MightyTips)
• Draw: approximately 3.70–3.80 (MightyTips)
• Villarreal to win: longer odds, around 4.20–4.30 (MightyTips)

Other markets:

• Both Teams to Score: likely “Yes” given Spurs’ attacking capability and Villarreal’s willingness to press in open phases. (Sportsgambler)
• Total Goals Over/Under 2.5: Over 2.5 seems probable in several previews. (Sportsgambler)

What to Watch / Key Factors

• Which Tottenham shows up: their sharper, high-energy side or the less consistent version. Spurs have alternated good and poor performances so far. (The Standard)
• Villarreal’s ability to cope with Spurs’ press and pace, especially with missing players in both defence and attack.
• Impact from new signings or fringe players: how Muani, Simons, Bergvall might contribute.
• Game management: set-pieces, defensive discipline, and how each side responds to periods of pressure.

If you like, I can also pull up odds from betting sites local to Nigeria, or predictions based on Nigerian sports analysts, so you get more region-tailored insight. Do you want that?